Rosart Tablet 25mg (Losartan Potassium) x50

Rosart Tablet 25mg contains Losartan Potassium, an angiotensin receptor blocker (ARB) used to treat high blood pressure and protect kidneys in diabetic patients. This medication effectively lowers blood pressure and reduces cardiovascular risks.

Uses

Rosart Tablet treats hypertension in adults and children over 6 years. It’s used for kidney protection in Type 2 diabetic patients with nephropathy, reduces stroke risk in hypertensive patients with left ventricular hypertrophy, and helps manage heart failure when ACE inhibitors are not tolerated.

Benefits

• Effectively lowers blood pressure without affecting heart rate
• Protects kidneys from diabetes-related damage
• Reduces risk of stroke and heart attack
• Well-tolerated with fewer side effects than ACE inhibitors
• Does not cause persistent dry cough
• Provides 24-hour blood pressure control
• Improves cardiovascular outcomes in high-risk patients
• Can be combined with other antihypertensive medications
• Suitable for patients who cannot tolerate ACE inhibitors

How It Works

Rosart blocks angiotensin II receptors, preventing this hormone from constricting blood vessels and stimulating aldosterone release. This action reduces peripheral vascular resistance, lowers blood pressure, and decreases strain on the heart. The medication also provides renal protection by reducing glomerular pressure.

Dosage

Take Rosart at the same time daily, with or without food. Dosage may be adjusted based on blood pressure response.

Duration of Action

Rosart begins lowering blood pressure within 1-3 hours of administration, with peak effects occurring at 3-6 hours. Its antihypertensive effect lasts 24 hours, allowing once-daily dosing. Maximum blood pressure reduction typically occurs after 3-6 weeks of regular treatment.

Side Effects

Most patients tolerate Rosart well. Common side effects include dizziness, fatigue, and upper respiratory infections. Some patients may experience headache, back pain, or diarrhea. Rare but serious effects include hyperkalemia, kidney dysfunction, or severe hypotension, especially with first dose.

Warning

Rosart can cause serious harm or death to developing fetus when used during pregnancy. Monitor kidney function and potassium levels regularly. May cause excessive blood pressure drop in volume-depleted patients. Not recommended for patients with severe liver impairment or bilateral renal artery stenosis.

Pregnancy and Breastfeeding

Rosart is contraindicated during pregnancy due to risk of fetal harm and death. Women of childbearing age should use effective contraception. It’s unknown if Losartan passes into breast milk, so nursing mothers should discontinue breastfeeding or the medication based on importance to mother.

Interaction

• May increase lithium levels leading to toxicity
• Enhanced hypotensive effects with other blood pressure medications
• Possible increased potassium levels with potassium supplements or salt substitutes
• May reduce effectiveness of certain pain medications
• Alcohol may enhance blood pressure lowering effects

Precaution

Monitor kidney function and electrolytes regularly, especially in elderly patients or those with kidney disease. Use cautiously in patients with liver impairment, heart failure, or volume depletion. Avoid potassium supplements unless specifically prescribed. Rise slowly from sitting or lying positions to prevent dizziness.

Important Information

Rosart is a prescription medication requiring regular monitoring. Take exactly as prescribed even if feeling well, as high blood pressure often has no symptoms. Continue taking unless instructed otherwise by your doctor. Store at room temperature away from moisture and heat. Maintain regular medical appointments to monitor effectiveness and side effects.